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在喘儿童中,峰值呼气流变化和喘恶化之间的关系
Xiongbin Chen1, Peng Han1, Yan Kong1
1Respiratory Department, Beijing Children's Hospital, Capital Medical University, China National Clinical Research Center of Respiratory Diseases, National Center for Children's Health, Beijing, China, 100045.
BMC pediatrics
|April 27, 2024
概括
在患有喘的儿童中,高峰呼气流 (PEF) 在症状出现前大约1.34天就会减少. 监测PEF可以帮助预测和管理喘恶化,特别是那些由空气污染引发的.
科学领域:
- 儿科肺病学 儿科肺病学
- 呼吸系统医学 呼吸系统医学
- 喘管理 喘管理
背景情况:
- 喘是儿童常见的慢性呼吸道疾病.
- 有效的喘行动计划旨在预防喘恶化.
- 在症状感知不良的儿童中,评估恶化是具有挑战性的.
研究的目的:
- 为了确定患有喘的儿童是否表现出急性恶化之前的峰值呼气流 (PEF) 的变化.
- 评估儿科患者PEF变化和喘恶化之间的关系.
主要方法:
- 来自电子中国儿童喘行动计划 (e-CCAAP) 数据库 (2017-2021) 数据的回顾性分析.
- 包括喘儿童连续14天进行PEF测量.
- 在恶化组和对照组之间比较PEF%的变化.
主要成果:
- 在喘症状出现前大约1.34天观察到PEF的下降.
- 没有并发症状的PEF降低的患者表现出最显著的PEF下降.
- 上呼吸道感染是最常见的恶化原因;空气污染导致PEF变化显著增加 (P<0.05).
结论:
- 患有喘的儿童在症状表现之前显示PEF的下降.
- 建议在早期干预和加强喘治疗时对PEF进行监测.
- 空气污染是导致喘恶化期间PEF变化的重要因素.
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