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Updated: Jun 27, 2025

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绘制C-linker域对CNBD通道门极性的贡献

Jenna L Lin1, Yongchang Chang2, Debanjan Tewari2

  • 1Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri; Center for the Investigation of Membrane Excitability Diseases, Washington University School of Medicine, St. Louis, Missouri; Graduate Program in Biochemistry, Biophysics, & Structural Biology, Washington University School of Medicine, St. Louis, Missouri.

Biophysical journal
|April 28, 2024
PubMed
概括

周期性核酸结合域 (CNBD) 离子通道家族的C终端域和C链接器区域显著影响它们的门极性. 超极化激活通道的关键是C-链接器间子单元接口内的相互作用残留物.

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