抗精神病药物的处方:智力/发育障碍的青少年与没有智力/发育障碍的青少年相比
Sandra Marquis1, N Esmé Marquis2, Yona Lunsky3
1School of Nursing, University of British Columbia, T201-2211, Wesbrook Mall, Vancouver, BC, V6T 2B5, Canada. smarquis@uvic.ca.
Journal of autism and developmental disorders
|April 28, 2024
概括
智力/发育障碍 (IDD) 的年轻人在医疗保健过渡期间更有可能接受抗精神病药物和甲胺. 这凸显了IDD年轻人的严重健康差异.
科学领域:
- 医疗保健服务研究 医疗服务研究
- 精神病学是一个精神病学.
- 发育儿科 发育儿科
背景情况:
- 智力/发育障碍 (IDD) 的年轻人在从儿科到成人医疗保健的过渡期间面临着独特的挑战.
- 抗精神病药物经常被处方用于行为和精神疾病,但具有显著的代谢风险.
研究的目的:
- 为了比较在医疗保健过渡期间在IDD和没有IDD的年轻人中开放的抗精神病药和甲福明.
- 检查不同类型的IDD的抗精神病使用情况,包括自闭症,胎儿酒精综合征 (FAS) 和唐氏综合征.
主要方法:
- 对2010-2019年人口级行政卫生数据的分析.
- 包括年龄在15-24岁的年轻人,比较那些有和没有IDD.
- 多变量逻辑回归用于计算药物发行调整的几率比率.
主要成果:
- 与没有IDD的年轻人相比,IDD的年轻人接受抗精神病药物 (aOR7.13) 和甲福明 (aOR3.74) 的几率明显更高.
- 在患有IDD的年轻人中增加了抗精神病药物的处方,即使在控制精神病诊断时也持续存在.
- 在IDD亚组中,患有自闭症,FAS和"其他"IDD诊断的年轻人使用抗精神病药物的几率高于唐氏综合征患者.
结论:
- 患有IDD的年轻人在医疗保健过渡期间经历了更高的抗精神病药物和甲福明处方率.
- 这些发现强调了严重的健康差异和针对IDD的年轻人进行有针对性的干预的需要.
- 需要进一步的研究来了解这些处方模式的驱动因素及其长期健康后果.
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