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Updated: Jun 27, 2025

Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase
07:27

Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase

Published on: April 29, 2010

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复制性聚合酶δ的Pold4亚单元在破碎的模板上促进了分叉减速

Kota Kojima1, Hiromori Ohkubo1, Ryotaro Kawasumi1

  • 1Department of Chemistry, Graduate School of Science, Tokyo Metropolitan University, Minamiosawa 1-1, Hachioji-shi, Tokyo 192-0397, Japan.

DNA repair
|April 28, 2024
PubMed
概括

DNA聚合酶三角酶的Pold4子单元在滞后链复制过程中促进复制叉反转,防止双链断裂 (DSB). 这一发现澄清了DNA修复和复制忠实性的关键机制.

关键词:
在Camptothecin的营地里.造成的DNA损伤是DNA损伤.叉子反转 叉子反转复制复制复制复制复制复制复制单链断裂器 单链断裂器

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