住院治疗心房动或动后的长期结果
Linh Thi Hai Ngo1,2, Yang Peng1,2, Russell Denman2
1Faculty of Medicine, The University of Queensland, 627 Rode Road, Chermside, Queensland 4032, Australia.
European heart journal
|April 28, 2024
概括
住院治疗心房动 (AF) 和动严重影响长期存活率,导致预期寿命大幅下降. 复发性AF/flutter和相关的心血管事件,如心力衰竭和中风是常见的,需要改进的治疗策略.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 前庭动 (AF) 和动是住院治疗的常见原因.
- 这些心脏事件后的长期结果仍然不确定.
- 这项研究调查了急性AF或飞住院后的10年预后.
研究的目的:
- 评估因心房动 (AF) 或动而住院后的长期存活率和预期寿命.
- 评估非致命结局的发生率,包括因心血管事件重新住院的情况.
- 为了确定AF/浮动的再住院率和导管切除的利用率.
主要方法:
- 分析了260,492名在澳大利亚和新西兰住院的成年患者,他们被诊断为初级AF或飞 (2008-2017).
- 利用卡普兰-梅尔方法和灵活的参数生存模型来估计生存和预期寿命.
- 采用竞争风险模型来评估非致命的结果,并考虑死亡率.
主要成果:
- 观察到高死亡率,在10年生存率为55.2%,预期寿命平均损失2.6年.
- 常见的再住院病例包括心力衰竭 (16.8%),中风 (11.0%) 和心肌梗塞 (7.1%).
- 在10年内,41.2%的AF/浮动再次入院;导管切除仅在6.5%的患者中进行.
结论:
- 住院治疗AF或飞与显著减少预期寿命和高死亡率有关.
- 复发性AF/飞,心力衰竭和中风是住院后经常发生的事件.
- 导管切除的不频繁使用表明需要加强AF/浮动管理的治疗策略.
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