饮食与多发性硬化症的疾病进展和症状之间的关联:观察性研究的系统审查
Eduard Martinez Solsona1, Thanasis Tektonidis1, Jeanette C Reece2
1Oxford Brookes Centre for Nutrition and Health, Oxford, United Kingdom.
Multiple sclerosis and related disorders
|April 28, 2024
概括
饮食质量可能会影响多发性硬化症 (MS) 症状,特别是生活质量和残疾. 需要更多的前性研究来证实饮食对MS进展和结果的影响.
科学领域:
- 神经学 神经学
- 营养科学 营养科学
- 系统审查是系统的审查.
背景情况:
- 在患有多发性硬化症 (pwMS) 的人群中,饮食修改是常见的,但在建议方面没有达成共识.
- 观察性研究表明饮食与MS进展之间存在联系,但缺乏系统的证据综合.
研究的目的:
- 系统地审查有关饮食和MS进展的观察性研究.
- 综合有关饮食与多发性硬化症症状和临床结果的证据.
主要方法:
- 在遵守PRISMA指南的基础上进行系统审查.
- 搜索了多个数据库,直到2023年7月,包括引用检查.
- 包括使用饮食质量评分/指数的研究;不包括单个食物/营养素.
- 使用纽卡斯尔-太华尺度评估偏差风险.
主要成果:
- 包括32项研究 (20项截面研究,12项前性研究).
- 常见的结果:残疾,生活质量,疲劳,抑郁,复发,焦虑,MRI.
- 未来研究表明,饮食质量可能与生活质量和残疾有关.
结论:
- 观察数据表明饮食和多发性硬化症症状之间存在联系,特别是生活质量和残疾.
- 对其他成员国结果的影响需要进一步调查.
- 需要更多的前性和干预性研究来证实饮食与MS的关联.
相关概念视频
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
331
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
331
Psychoneuroimmunology: Diabetes and Cancer
28
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
28
Chronic Bowel Disorders: Introduction
446
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
446
Genome-wide Association Studies-GWAS
13.4K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
GWAS does not require the identification of the target gene involved in...
13.4K


