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Updated: Jun 27, 2025

Generation of Human Nasal Epithelial Cell Spheroids for Individualized Cystic Fibrosis Transmembrane Conductance Regulator Study
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一个由促进剂依赖的上游激活剂在各种表皮细胞类型中增加了CFTR的表达

Giuliana C Coatti1, Nirbhayaditya Vaghela1, Pulak Gillurkar1

  • 1Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.

Biochimica et biophysica acta. Gene regulatory mechanisms
|April 28, 2024
PubMed
概括

研究人员发现了一种促进囊性纤维化转膜导电性调节器 (CFTR) 基因表达在特定细胞中的新方法. 这种涉及 cis 调节元和 CRISPRa 的新机制,可以为囊性纤维化 (CF) 提供新的治疗方法.

关键词:
在CFTR中,CFTR是最重要的.克里斯普拉是一个.关联调节元素的关联调节元素.这是一种流行病.荷尔蒙的调节 荷尔蒙的调节开放的染色素是开放的

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