姿势和CPAP对鼻腔气流的影响
Ahmad T Hamdan1, Sarin Rungmanee2, Nithita Sattaratpaijit2
1Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, Milwaukee, WI, United States; Department of Biomedical Engineering, Marquette University & The Medical College of Wisconsin, Milwaukee, WI, United States.
Respiratory physiology & neurobiology
|April 28, 2024
概括
阻塞性睡眠呼吸暂停 (OSA) 的持续正气道压力 (CPAP) 并没有显著影响鼻气流或阻力. 转变为仰卧姿势改善了鼻腔气流对称性,而CPAP使用并没有改变这一点.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 睡眠医学 睡眠医学
- 呼吸系统生理学 呼吸系统生理学
背景情况:
- 使用持续正气道压力 (CPAP) 的阻塞性睡眠呼吸暂停 (OSA) 患者经常报告鼻腔副作用,如干燥和阻塞.
- 导致这些CPAP诱导的鼻症状的潜在生理机制尚不清楚.
- 一个假设表明,CPAP会扰乱鼻子循环,消除其休息阶段并导致干燥.
研究的目的:
- 调查CPAP对OSA患者鼻气流动力学和鼻循环功能的影响.
- 为了确定CPAP是否会改变鼻腔阻力,空气流分区或鼻腔透度.
主要方法:
- 对31名OSA患者进行了鼻腔计量测量.
- 测量是在坐着,躺着和CPAP后躺着的位置 (10cmH2O10分钟).
- 评估了鼻腔阻力,单边气流和鼻孔之间的空气流分区.
主要成果:
- 从坐到卧的姿势变化显著增加了鼻孔之间的气流对称性.
- 使用CPAP并没有导致鼻腔整体抵抗的显著变化.
- CPAP并没有显著改变单边鼻腔空气流或空气流分割的对称性.
结论:
- 卧卧状态的位置变化立即增强OSA患者的鼻腔气流对称性.
- 在10cmH2O的CPAP治疗似乎不会对鼻气流动力学或鼻阻力产生负面影响.
- CPAP保留了通过采取仰卧姿势实现的改善的鼻腔气流对称性.
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