酒精消费和心力衰竭的进展在那些有心力衰竭或心脏衰竭前风险的人群中
Bethany Wong1, Ashe Moore2, Ken McDonald3
1St Vincent's University Hospital, Elm Park, Dublin, Ireland; School of Medicine, University College Dublin, Dublin, Ireland.
Journal of cardiac failure
|April 28, 2024
概括
中度至高度的酒精消费 (>70g/周) 显著增加了心力衰竭前期心力衰竭 (HF前期) 患者心力衰竭进展的风险. 低酒精摄入量没有对心力衰竭进展产生保护作用.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 酒精研究 酒精研究
背景情况:
- 研究酒精消费与心脏健康之间的联系对于预防策略至关重要.
- 欧洲老年人群面临心力衰竭前期风险或心力衰竭前期风险需要特别注意生活方式因素.
- 左心室功能障碍 (LVD) 和症状性高血压是老年人群的重大健康问题.
研究的目的:
- 为了确定酒精摄入量和LVD和/或症状性HF的进展之间的剂量反应关系.
- 分析老年欧洲人口与现有风险因素或HF前的这种关系.
- 为了评估低酒精消费的潜在保护作用.
主要方法:
- 纵向观察性研究分析了STOP-HF试验后续数据.
- 包括记录酒精摄入量和心声回声图的患者,不包括以前的饮酒者.
- 评估酒精摄入量 (无,≤70g/周,>70g/周) 和中位数5.44年的HF进展.
主要成果:
- 中等至高的酒精摄入量 (>70g/周) 与患有HF前患者中HF进展的风险增加4.9倍有关.
- 在调整了多种临床和遗传因素后,这种关联仍然显著.
- 在高风险患者中,酒精使用与HF进展之间没有发现任何关联,也没有观察到低酒精摄入量的保护性益处.
结论:
- 中度至高度的酒精消费是患有HF前的个体中HF进展的危险因素.
- 低酒精消费似乎没有提供保护性益处,防止HF的进展.
- 这些研究结果强调了限制心脏病患者饮酒的重要性.
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