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在急性胰腺炎中,心率持续升高和90天死亡率
Shan Xie1, Fuxing Deng2, Nuobei Zhang1
1Department of Gastroenterology, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, China.
长期心率升高 (peHR) 是急性胰腺炎患者90天死亡的重要风险因素. 这一发现强调了监测重症监护病房内心率的重要性,以改善患者的治疗结果.
科学领域:
- 关键护理医学 关键护理医学
- 心脏病学 心脏病学
- 胃肠病学 胃肠病学
背景情况:
- 长时间心率升高 (peHR) 是重症患者已知的预后指标.
- peHR与急性胰腺炎的结果之间的关联仍未得到充分研究.
研究的目的:
- 研究急性胰腺炎患者的peHR和90天死亡率之间的关系.
- 确定peHR作为这种患者群体中死亡率的潜在独立风险因素.
主要方法:
- 使用了密集护理IV (MIMIC-IV) 数据库中的多参数智能监控.
- 定义的peHR是心率>100 bpm至少在12个连续小时中的11个.
- 采用考克斯回归分析和卡普兰-梅尔生存曲线来评估死亡风险.
主要成果:
- 总共有364名急性胰腺炎患者经历了peHR (48.9%).
- 90天死亡率为25%,peHR是一个独立的风险因素 (HR,1.98;P<0.001).
- 卡普兰-梅尔曲线显示,患有peHR的患者的90天生存率显着较低 (65.1%与84.5%相比).
结论:
- 长期心率升高与急性胰腺炎的ICU患者90天死亡率的增加显著相关.
- 在这个群体中,peHR 作为预后不佳的独立预测因素.
- 持续监测心率可能对急性胰腺炎的风险分层和管理至关重要.
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