立体治疗预处理质量保证中的剂量测量系统:相关性协议和目标体积依赖性
Sivakumar Muthu1,2, Gopinath Mudhana1
1Department of Physics, School of Advanced Sciences, Vellore Institute of Technology, Chennai - 600 127, India.
Asian Pacific journal of cancer prevention : APJCP
|April 29, 2024
概括
立体性放射外科手术 (SRS/SRT) 的治疗前质量保证 (QA) 显示,不同检测器类型之间的对点和平面剂量评估的相关性较弱. 在检测器类型中发现了强烈的相关性,强调对SRSQA结果的谨慎解释.
科学领域:
- 医学物理 医学物理
- 辐射瘤学 辐射瘤学
- 辐射疗法质量保证 辐射疗法质量保证
背景情况:
- 立体辐射手术 (SRS) 和立体辐射疗法 (SRT) 等立体辐射疗法需要严格的治疗前质量保证 (QA).
- 对于SRS/SRT QA,使用了各种检测器,但它们的检测器间协议和与治疗计划系统 (TPS) 计算的相关性对于确保治疗准确性至关重要.
研究的目的:
- 调查接受SRS/SRT的100名癌症患者的治疗前质量保证.
- 评估用于点剂量和平面剂量测量的不同探测器之间的一致性和相关性.
- 评估目标体积对质量保证结果和探测器性能的影响.
主要方法:
- 对于SRS/SRT治疗,使用6MV SRS光束和Eclipse v13.6 TPS.进行了QA.
- 使用0.01cm3和0.13cm3的电离室进行点剂量测量.
- 平面剂量验证使用了Gafchromic EBT-XD膜和aS1000门户成像仪.
- 分析对比了点剂量协议,马传递率,以及与室体积,探测器类型和剂量协议的相关性.
主要成果:
- 总体而言,随着目标体积的增加,点剂量协议得到了改善,但体积>10cm3.3的例外情况除外.
- 在TPS和两室测量剂量之间发现了显著的差异 (p<0.05).
- 马通过率与目标体积有所改善,除了使用EBT XD膜的>10cm3组外.
- 在10cm3 (p<0.05) 的目标体积上,EBT XD薄膜显示出比aS1000更好的一致性.
- 在点剂量和平面剂量分析的检测器类型中存在强烈的相关性,但在不同检测器类型之间发现了弱相关性.
结论:
- 对于SRS/SRT的治疗前质量评估表明,在点和平面剂量评估中,不同检测器类型之间的相关性较弱.
- 在各种质量保证指标的特定检测器类型中观察到强烈的相关性.
- 这些发现强调,由于检测器间的变化,需要谨慎解释SRS QA结果.
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