节省与吞相关的结构减少了口腔癌中放射治疗后的腹
Chanin Wasuthalainun1, Phawin Keskool1, Janjira Petsuksiri2
1Department of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
在口腔瘤放射治疗期间,节省特定的吞结构是关键. 较低的辐射剂量到喉收缩器,喉和喉可以改善治疗后的吞功能.
科学领域:
- 辐射瘤学 辐射瘤学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 吞障碍 吞障碍 吞障碍
背景情况:
- 口腔癌放射治疗可能导致治疗后的消化不良.
- 识别关键的吞相关结构 (SRSs) 对于维护功能至关重要.
- 了解SRS的剂量反应关系可以优化治疗计划.
研究的目的:
- 确定特定的吞相关结构 (SRSs),其辐射剂量预测了口腔癌患者的放射治疗后食障碍.
- 为了将辐射剂量与FEES评估的吞功能的单个SRS相关联.
主要方法:
- 对29名用放射治疗治疗的口腔癌患者的回顾性分析.
- 吞的灵活内镜评估 (FEES) 和吞障碍分级至少在放射治疗后一年进行.
- 将平均辐射剂量重新计算为SRS和与FEES得分的相关性.
主要成果:
- 向下喉缩器,喉和喉的辐射剂量显著预测了半固体和液体的食障碍.
- 消化管入口剂量预测了只有液体饮食的吞结果.
- 在参与者中使用了不同的放射治疗技术 (2D,3D-CRT,IMRT).
结论:
- 在放射治疗期间,省略下喉缩器,喉和喉对于改善口癌幸存者的吞结果至关重要.
- 这一发现支持需要精确的辐射规划,以尽量减少对这些关键的SRSs的剂量.
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