Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

400
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
400
Inflammatory Response01:28

Inflammatory Response

2.0K
An inflammatory response is a localized, nonspecific immune reaction that occurs when a tissue is injured. It is characterized by redness, swelling, heat, and pain, which are commonly called the cardinal signs and symptoms of inflammation. Inflammation can sometimes result in a loss of function.
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
2.0K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Real-world effectiveness of rezvilutamide plus androgen deprivation therapy in patients with high-volume metastatic hormone-sensitive prostate cancer: a retrospective multicenter cohort study.

Translational andrology and urology·2026
Same author

A mineral-electron-driven photophosphorylation has potential impacts on photosynthetic bacteria evolution and ecological environment changes.

Journal of advanced research·2026
Same author

Bottom-Up Absorptive and Stretchable Plasmonic Tape for Field-Deployable In Vivo Fruit Safety Surveillance.

ACS sensors·2026
Same author

An Open Comparative Study on the Effectiveness of Customized and Non-Customized Sound Therapy for Tinnitus Patients.

Journal of clinical medicine·2026
Same author

Ready-to-use, in situ formed collagen/RGD/hyaluronic acid hydrogel: accelerating full-thickness wound healing.

Biomaterials·2026
Same author

KAN-PROSPECT: a Kolmogorov-Arnold Networks-integrated framework for predicting the effects and adverse reactions of natural products via transfer learning.

Scientific reports·2026

相关实验视频

Updated: Jun 27, 2025

On-Chip Endothelial Inflammatory Phenotyping
12:43

On-Chip Endothelial Inflammatory Phenotyping

Published on: July 21, 2012

10.9K

勃起功能障碍中的炎症性细胞因子概况:双向的门德尔随机化.

Dongze Liu1, Zheng Qin2, Bocun Yi1

  • 1Department of Urology, National Key Specialty of Urology, Second Hospital of Tianjin Medical University, Tianjin Key Institute of Urology, Tianjin Medical University, Tianjin, China.

Frontiers in immunology
|April 29, 2024
PubMed
概括

干扰素诱导蛋白-10 (IP-10) 增加勃起功能障碍 (ED) 的风险,而干扰素-1受体对抗剂 (IL-1RA) 降低了风险. 这些炎症性细胞因子为ED治疗和预防提供了潜在的点.

关键词:
它们的IL-1ra.IP-10 标签:IP-10 标签:IP-10 标签:IP-10 标签:IP-10 标签:IP-10 标签:IP-10双向的门德尔式随机化这是勃起功能障碍.这是一种炎症性细胞因子.

更多相关视频

Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response
12:50

Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response

Published on: September 15, 2017

6.6K
An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents
06:55

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents

Published on: December 2, 2015

22.5K

相关实验视频

Last Updated: Jun 27, 2025

On-Chip Endothelial Inflammatory Phenotyping
12:43

On-Chip Endothelial Inflammatory Phenotyping

Published on: July 21, 2012

10.9K
Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response
12:50

Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response

Published on: September 15, 2017

6.6K
An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents
06:55

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents

Published on: December 2, 2015

22.5K

科学领域:

  • 遗传学 是一个遗传学.
  • 免疫学 免疫学 免疫学
  • 泌尿器科 泌尿器科 泌尿器科 泌尿器科

背景情况:

  • 炎症性细胞因子 (ICs) 与勃起功能障碍 (ED) 有关.
  • 在许多ED患者中观察到高水平的TNF-α,IL-6和IL-8.
  • 具体的IC和ED之间的因果关系需要进一步调查.

研究的目的:

  • 研究41种炎症性细胞因子 (ICs) 和勃起功能障碍 (ED) 之间的因果关系.
  • 通过使用孟德尔随机化 (MR) 方法来确定影响ED风险的特定IC.

主要方法:

  • 利用了来自8293名受试者的41个IC的全基因组关联研究 (GWAS) 数据.
  • 使用FINNGEN R9数据库进行ED结果数据 (2205例,164104项控制).
  • 应用了MR-Egger,逆方差加权 (IVW) 和加权中位数 (WM) 方法,以IVW作为主要分析.

主要成果:

  • 增加的干扰素诱导蛋白-10 (IP-10) 水平显著增加了ED风险 (OR=1.269,P=0.043).
  • 增加的互白素-1受体对手 (IL-1RA) 水平显著降低了ED风险 (OR=0.768,P=0.037).
  • 反向MR分析没有证实IP-10或IL-1RA的因果关系.

结论:

  • 炎症性细胞因子显著影响ED风险,IP-10作为风险因素,IL-1RA作为保护因素.
  • 针对特定炎症因子的有针对性的干预是ED治疗和预防的潜在策略.