在美国成年人中,饮食中的黄胺摄入量与高血压之间的关联
Yingying Wan1, Dan Ma2, Qinghua Shang1
1National Clinical Research Center for Chinese Medicine Cardiology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
饮食中所含的安托西亚宁和黄素-3-ols显示出降低高血压患病率的潜力. 适度摄入这些黄素可能有助于改善心血管健康,并降低成人高血压风险.
科学领域:
- 心血管健康 心血管健康
- 营养科学 营养科学
- 流行病学 流行病学
背景情况:
- 高血压是心血管疾病的重要危险因素.
- 饮食中的黄素以抗炎和抗氧化物质的特性而闻名,可能有利于血管健康.
- 黄类药物消费与高血压患病率之间的联系需要进一步研究.
研究的目的:
- 为了研究饮食中黄酸盐摄入量与高血压患病率之间的关联.
- 探索特定的黄类子类,包括安东素和黄-3-ols.
- 分析基于人口的数据,寻找支持黄类药物与高血压关系的证据.
主要方法:
- 利用了来自2007-2010年和2017-2018年国家健康和营养检查调查 (NHANES) 的8010名成年人的数据.
- 采用加权后勤回归和加权限制立方线分析.
- 研究了特定黄类子类的总摄入量与高血压患病率之间的关系.
主要成果:
- 总安托西亚尼摄入量和高血压患病率之间观察到一个反向关联 (Q4 vs Q1: 0.81 [0.66,0.99],p=0.04).
- 在60岁以上的成年人中,高血压的患病率随着更高的抗生素摄入量而降低.
- 对于全方位的flavan-3-ol摄入量,发现了U形关系,Q3的反向关联 (Q3与Q1:0.79 [0.63,0.99],p=0.04) 和低于48.26毫克/天的负相关.
结论:
- 适度摄入总安东素和总黄素-3-ols与高血压患病率有负面关联.
- 这项以人口为基础的研究提供了证据,证明饮食中的黄类化合物在高血压管理中的有益作用.
- 研究结果表明,特定的黄类子类可能有助于降低高血压风险.
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