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Updated: Jun 27, 2025

The ITS2 Database
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序列和结构特定的tRNA通过hDUS2进行二氧化化

Jingwei Ji1, Nathan J Yu1, Ralph E Kleiner1

  • 1Department of Chemistry, Princeton University, Princeton, New Jersey 08544, United States.

ACS central science
|April 29, 2024
PubMed
概括

人类二uridine合成酶2 (hDUS2) 在tRNA中以特定的GU序列为指导,在U20处将尿素修改为二uridine (D). 这项研究还为发现hDUS2抑制剂用于癌症治疗提供了一个平台.

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