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关于自闭症谱系障碍的精神药物治疗的最新情况
Ramkumar Aishworiya1, Tatiana Valica1, Randi Hagerman1
1Medical Investigation of Neurodevelopmental Disorders (MIND) Institute, University of California Davis, 2825 50th Street, Sacramento, CA 95817, USA (Aishworiya, Valica, Hagerman, Restrepo); Khoo Teck Puat-National University Children's Medical Institute, National University Health System, 5 Lower Kent Ridge Road, Singapore 119074, Singapore; Department of Pediatrics, Yong Loo Lin School of Medicine, National University of Singapore, 1E Kent Ridge Road, Singapore 119228, Singapore (Aishworiya); Association for Children With Autism, Chisinau, Moldova (Valica); Department of Pediatrics, University of California Davis School of Medicine, 4610 X St, Sacramento, CA 95817, USA (Hagerman, Restrepo).
自闭症谱系障碍 (ASD) 的新向治疗方法正在出现,重点是神经生理学和遗传学. 这些有希望的方法很快可能会补充对核心ASD症状的行为干预措施.
科学领域:
- 神经科学是一个神经科学.
- 遗传学 是一个遗传学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 行为干预是自闭症谱系障碍 (ASD) 的首要治疗方法.
- 新兴的向治疗旨在解决ASD的潜在神经生理学问题.
- 遗传因素越来越被认为是未来ASD治疗的关键目标.
研究的目的:
- 审查目前对ASD的精神药物治疗方法.
- 讨论自闭症管理的新有针对性的方法.
- 检查核心症状和并发症的药物和补充剂.
主要方法:
- 对ASD的心理药物和向治疗方法的文献综述.
- 讨论特定的药物 (例如,甲胺,大麻,催产素,托菲尼提德) 和补充剂 (例如,硫法,N-乙半氨酸).
- 对常见的ASD并发症 (抗精神病药物,血清激素药物,α-2激动剂,兴奋剂) 的药物的审查.
主要成果:
- 几种新型药物和补充剂显示出对ASD治疗的希望.
- 针对脆弱X综合征 (FXS) 的向治疗为其他ASD形式提供了一个模型.
- 目前的治疗方法也有效地解决了常见的并发病症.
结论:
- 针对神经生理学和遗传学的向性治疗正在推动自闭症管理.
- 未来的疗法可能包括对ASD的基因疗法.
- 行为和向治疗的结合可能是ASD护理的未来.
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