术后预防性抗生素在乳腺缩小乳房整形术中的使用:单一中心回顾性队列研究
Véronique M Doucet1,2, Jakob J Weirathmueller1, Graham J McLeod1,2
1Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Plastic surgery (Oakville, Ont.)
|April 29, 2024
概括
手术后的预防性抗生素在缩小乳腺造型术 (BRM) 后没有显著减少手术部位感染 (SSI). 在预防SSI方面,单次手术前剂量与更长的疗程同样有效.
科学领域:
- 整形外科 整形外科 整形外科
- 预防传染病 预防传染病
背景情况:
- 乳房缩小乳房整形术 (BRM) 是一种常见的手术程序,用于治疗高乳房.
- 目前的实践往往包括预防性抗生素,但证据支持它们在预防手术部位感染 (SSIs) 的有效性是有限的.
研究的目的:
- 评估将术后预防性抗生素添加到单次手术前剂量的疗效,以预防BRM后的SSI.
主要方法:
- 对124个选择性BRM病例进行了回顾性分析.
- 两个组进行了比较:第一组接受了单次手术前静脉注射抗生素剂量;第二组接受了手术前剂量加上5天的口服抗生素疗程.
主要成果:
- 总体SSI率为5.6%. 这是一个很好的数字.
- 第1组的SSI率为8.1%,而第2组的SSI率为3.2% (P = .44).
- 第1组的整体并发症率为38.7%,第2组为19.4% (P = .03),而延迟伤口愈合是最常见的并发症.
结论:
- 加上术后预防性抗生素并没有显著降低BRM中SSI的发生率.
- 这项研究表明,单次手术前剂量可能足以用于BRM的感染预防.
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