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药剂师报告了精神病药物的QTc监测协议
Kathleen Harb1, Shaina Schwartz1, Julie Cooper1
1Clinical Sciences, High Point University Fred Wilson School of Pharmacy, High Point, USA.
Cureus
|April 29, 2024
概括
精神病药物可以延长QTc间隔,但监测的最佳实践尚不清楚. 一项调查揭示了多种QTc监测方法,药剂师主导的ECG显示了改善患者护理的潜力.
科学领域:
- 药理学 药理学是指药理学的学科.
- 心脏病学 心脏病学
- 精神病学是一个精神病学.
背景情况:
- 精神病药物,包括抗精神病药物和抗抑郁药,与QTc间隔延长有关,这是潜在的严重心脏副作用.
- 目前的临床实践缺乏关于监测和减轻使用这些药物的患者的QTc延长风险的标准化方法的共识.
研究的目的:
- 调查和分析 QTc 间隔监测当前的实践在患者处方精神病药物.
- 确定用于降低风险的方法,并了解实施监测协议所面临的挑战.
主要方法:
- 一项匿名电子调查分发给全国精神病药剂师组织的成员.
- 数据收集发生在2022年9月22日至12月15日,使用多选题的描述统计数据和基于理论的自由答案答案的定性分析.
主要成果:
- 只有11.4%的机构报告了QTc监测的正式协议;32.4%有非正式的过程,其中约一半是药物特定的.
- 精神病学临床药房专家在88.6%的机构存在,34.3%的机构允许药剂师订购心电图 (ECG).
- 关键主题包括药剂师主导的监测,患者转诊监测,以及实施有效QTc监测的重大障碍.
结论:
- 目前用于监测精神病药物治疗患者的QTc延长风险的方法各不相同,没有标准化.
- 赋予药剂师能够订购心电图的能力,为增强患者护理和推进管理QTc延长风险的实践提供了潜在的途径.
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