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Min Seo Choi^1,2, Ryeong Hwang Park¹, Joongyo Lee^3,4

¹Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Seoul, South Korea.

Advances in radiation oncology

|April 29, 2024

概括

持续的正气道压力 (CPAP) 和深呼吸喘息 (DIBH) 为左侧乳腺癌辐射疗法 (RT) 提供了类似的心脏剂量减少. CPAP是一种可行的DIBH替代品,具有可比的几何和剂量学效益.

科学领域:

辐射瘤学辐射瘤学
医学物理医学物理
乳腺癌治疗方法乳腺癌治疗方法

背景情况:

深呼吸喘息 (DIBH) 是一种常见的技术,用于减少心脏和肺部剂量在左侧乳腺癌放射治疗 (RT).
持续正气道压力 (CPAP) 是RT中呼吸运动管理的新兴技术,但与DIBH的直接比较有限.

研究的目的:

为了比较CPAP和DIBH技术在左侧乳腺癌放射治疗中的几何和剂量有效性.
为CPAP提供全面的证据,作为DIBH的潜在替代品.

主要方法:

35名左侧乳腺癌患者的回顾性分析.
在自由呼吸 (FB),CPAP (10 cmH2O) 和DIBH条件下获得的CT扫描计划.
卷积弧治疗规划与比较剂量计和几何分析,包括心脏到临床目标体积 (CTV) 距离.

主要成果:

CPAP和DIBH计划显示可比的平均心脏剂量 (1.05 Gy),明显低于FB (1.34 Gy).
与DIBH (4.73 Gy) 和FB (7.33 Gy) 相比,CPAP计划对左前下降动脉 (4.44 Gy) 的最大剂量是最低的.
在CPAP和DIBH之间,其他风险器官的剂量和心脏到心血管的距离是相似的;DIBH导致最大的肺体积.

结论:

CPAP和DIBH显示左侧乳腺癌RT的几何和剂量测量结果相似.
CPAP是一种有效和可行的技术,为心脏和肺部剂量管理提供了DIBH的可行替代方案.

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