微观结肠炎患者的随访和腹控制在1年后
Walker D Redd1, Chelsea Anderson1,2, Anne F Peery1,2
1Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Gastro hep advances
|April 29, 2024
概括
微观结肠炎 (MC) 管理需要改进,因为许多患者仍然不知道自己的诊断或经历持续的症状. 与其他慢性腹引起的对照报告的症状比MC病例更严重.
科学领域:
- 胃肠病学 胃肠病学
- 内部医学 内部医学
- 临床研究 临床研究
背景情况:
- 微观性结肠炎 (MC) 是慢性腹的常见原因,但其临床轨迹尚未确定.
- 在现实实践中了解MC患者的管理对于改善结果至关重要.
研究的目的:
- 在常规临床实践中评估微观结肠炎患者的治疗方法.
- 为了比较MC患者的症状负担与那些经历其他形式的慢性腹的一年随访.
主要方法:
- 一项病例控制研究,涉及接受腹评估结肠镜检查的患者.
- 由研究病理学家对患者进行MC病例和非MC对照的分类.
- 一年后的结肠镜面试与病例 (n=74) 和对照 (n=162) 进行,以评估诊断意识,药物使用和症状严重程度.
主要成果:
- 在一年的随访中,10%的MC病例不知道他们的诊断,60%接受了治疗腹的药物.
- 患有MC的病例报告了包括便急迫 (40%),体重减轻 (32%) 和便失禁 (21%) 在内的症状; 46%的人接受了布德索尼德治疗.
- 对照组表现出比MC病例更糟糕的症状,由更高的微观结肠炎疾病活动指数得分 (中位数为3.0比2.3) 和更频繁的便,急迫性,失禁和腹痛表明.
结论:
- 有机会提高微观结肠炎的管理,这是一个慢性疾病.
- 提高患者对MC诊断的认识和持续症状管理是干预的关键领域.
- 与MC相比,控制其他慢性腹疾病的症状可能需要不同的策略.
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