相关实验视频
Updated: Jun 27, 2025
08:40
Chronic Salmonella Infection Induced Intestinal Fibrosis
Published on: September 22, 2019
7.1K
心血管并发症和炎症性肠病:原因和后果
Preetika Sinh1, Raymond K Cross2
1Division of Gastroenterology and Hepatology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Gastroenterology & hepatology
|April 29, 2024
概括
患有炎症性肠病 (IBD) 的患者面临更高的心血管疾病 (CVD) 风险,即使没有传统因素. 治疗慢性炎症可能会降低这种风险,但需要更多的研究.
科学领域:
- 心血管医学 心血管医学
- 胃肠病学 胃肠病学
- 免疫学 免疫学 免疫学
背景情况:
- 患有炎症性肠病 (IBD) 的患者患有心血管疾病 (CVD) 的风险增加,包括心肌梗塞和中风.
- 在IBD患者中,心血管疾病通常在较年轻时出现,并且与活跃疾病有关,与传统的心血管疾病风险概况有所不同.
- IBD和动脉样硬化心血管疾病 (ASCVD) 都具有慢性炎症的特征,这表明共享的炎症途径驱动IBD中的ASCVD风险.
研究的目的:
- 讨论患有炎症性肠病 (IBD) 的患者心血管疾病 (CVD) 的原因.
- 探索改变IBD患者心血管疾病后果的潜在策略.
- 突出需要针对IBD中ASCVD的具体指导方针和风险评估工具.
主要方法:
- 文献综述和现有IBD和CVD研究的综合.
- 分析慢性炎症在IBD患者ASCVD发展中的作用.
- 讨论IBD药物对ASCVD风险的影响.
主要成果:
- 在IBD中,慢性炎症是增加ASCVD风险的一个重要因素.
- IBD药物可能具有不同的效果,增加或减少ASCVD风险.
- 目前关于ASCVD的指导方针和评估方法对于IBD患者缺乏.
结论:
- 炎症性肠病显著增加心血管疾病的风险,特别是在患有活跃疾病的年轻患者中.
- 针对炎症可能是一个可行的策略,以减轻ASCVD在IBD的风险,尽管需要进一步的数据.
- 制定ASCVD风险评估和IBD风险管理的具体指南至关重要.
更多相关视频
相关概念视频
01:30Inflammatory Bowel Disease II: Crohn's Disease
222
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
222
01:27Inflammatory Bowel Disease I: Ulcerative Colitis
172
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
172
01:17Chronic Bowel Disorders: Introduction
446
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
446
01:30Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
331
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
331
01:29Inflammatory Bowel Disease IV: Pharmacological Management
127
Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
Pharmacologic...
127
01:17Irritable Bowel Syndrome I: Introduction
272
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
272