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Updated: Jun 27, 2025

Recapitulation of an Ion Channel IV Curve Using Frequency Components
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Published on: February 8, 2011

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CAVIN1介导的hERG动力学:药物诱导的长QT的个体间变异的新机制

Zeina R Al Sayed1, Céline Pereira1, Rémi Le Borgne2

  • 1PARCC, INSERM (Z.R.A.S., C.P., C.J., N.M., J.-S.H.), Université Paris Cité, Paris, France.

Circulation
|April 29, 2024
PubMed
概括

药物诱导的QT延长 (diLQT) 敏感性与hERG通道动态有关. CAVIN1调节hERG通道转位,影响患者对延长QT的药物的敏感性.

关键词:
洞穴动物与药物相关的副作用和不良反应诱导多能干细胞长时间QT综合征肌细胞,心脏

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