在不同高度的静脉血栓栓塞的概况
Shiqiang Xiong1, Jun Hou1, Haixia Yang2
1Department of Cardiology, Chengdu Third People's Hospital, Affiliated Hospital of Southwest Jiao Tong University, Chengdu, China.
High altitude medicine & biology
|April 29, 2024
概括
高海拔环境增加了静脉血栓塞栓症 (VTE),特别是肺栓塞 (PE) 的风险. 非常高的海拔高度显著增加了腿部深静脉血栓症 (DVT) 的风险,特别是在初次暴露时.
科学领域:
- 环境医学 环境医学
- 心血管健康 心血管健康
- 高度生理学 高度生理学
背景情况:
- 静脉血栓塞栓症 (VTE) 构成严重的健康风险.
- 高海拔 (HA) 环境带来了独特的生理挑战.
- 了解不同高度的VTE发病率对于公共卫生至关重要.
研究的目的:
- 调查高海拔 (HA) 和非常高海拔 (VHA) VTE的发病率和危险因素.
- 在肺栓塞 (PE) 患者中,将HA和VHA之间的深静脉血栓塞 (DVT) 风险进行比较.
主要方法:
- 在2004年至2022年期间被诊断患有DVT或PE的患者的回顾性分析.
- 在中国叶进行的研究,比较了HA和VHA的VTE概况.
- 统计分析以确定DVT风险的几率比率 (OR) 和置信区间 (CI).
主要成果:
- 与HA患者相比,在VHA的PE患者表现出明显更高的下肢DVT风险 (OR 16.3 [95% CI 1.2-223.2],p = 0.036) 与HA患者相比.
- 由于VHA的恶劣环境条件加剧了VTE的风险.
- 观察到风险增加,特别是在适应VHA的早期阶段.
结论:
- 非常高的海拔高度会显著增加肺栓塞 (PE) 和相关深静脉血栓塞 (DVT) 的风险.
- 在VHA的环境压力因素对VTE的发展产生了重大影响.
- 加强预防策略和及时的医疗干预对于VHA地区的个人来说至关重要.
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