纳米维生素E改善了 brojler的抗氧化能力
Jinghui Zhou1, Zhipeng Li1, Wei Guo1
1College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
Journal of animal science
|April 29, 2024
概括
与普通维生素E (VE) 相比,纳米维生素E (NVE) 显著提高肉的抗氧化能力和血持久性. 尽管对整体生长性能没有影响,但NVE通过增加抗氧化酶活性和吸收率来改善肉健康.
科学领域:
- 禽类的营养和生理学
- 在动物料中纳米技术
- 抗氧化剂研究的研究.
背景情况:
- 维生素E (VE) 是家禽的重要抗氧化剂,但其疏水性限制了生物利用性.
- 纳米技术提出了一种方法来提高像VE这样的脂性化合物的吸收和稳定性.
- 氧化应激会对家禽的健康和表现产生负面影响.
研究的目的:
- 评估不同维生素E (VE) 来源和水平对肉生长,抗氧化状态和药理动力学的影响.
- 为了比较纳米封装VE (NVE) 与Arbor Acres (AA) brojler中的常规VE (RVE) 的疗效.
- 研究纳米化对VE吸收的影响及其在 brojlers中的药物动力学特征.
主要方法:
- 384只Arbor Acres (AA) 被分为四组,接受30或75 IU/kg的常规VE或纳米VE (NVE).
- 测量了生长表现,抗氧化酶活性 (SOD,GSH-Px) 和甲 (MDA) 水平.
- 分析了肠道和血中的VE度,以及药理动力学参数 (AUC,MRT,t1/2z,Cmax).
主要成果:
- 饮食中的VE来源并没有显著影响肉的生长性能.
- 与较高剂量 (75 IU/kg) 相比,较低剂量 (30 IU/kg) 的 VE 改善了平均每日增益和料转换率.
- 与RVE相比,NVE显著增强了抗氧化能力 (更高的SOD和GSH-Px,更低的MDA) 和改善了VE吸收率和血药理学参数 (AUC0-∞,MRT0-∞,t1/2z,Cmax).
结论:
- 纳米化维生素E (VE) 改善了其在肉血中的吸收和持久性,增强了其抗氧化功能.
- 纳米维生素E (NVE) 在肉中表现出优异的抗氧化作用,特别是在氧化应激条件下.
- 虽然VE水平会影响生长,但纳米封装是最大限度地提高VE在家禽中的生物可用性和有效性的关键.
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