尾切除术与急性尾炎的抗生素治疗相比
Brett Doleman1, Siv Fonnes2, Jon N Lund3
1Department of Surgery and Anaesthesia, Division of Medical Sciences and Graduate Entry Medicine, School of Medicine, University of Nottingham, Derby, UK.
The Cochrane database of systematic reviews
|April 29, 2024
概括
对于不复杂的尾炎,抗生素可能会导致更多的治疗失败,但伤口感染较少. 虽然一些患者避免了手术,但其他人可能会在以后需要手术,对住院时间的影响不确定.
科学领域:
- 一般外科 整体外科
- 传染性疾病 传染性疾病
背景情况:
- 急性尾炎是一种常见的手术紧急情况.
- 治疗选择包括尾切除术或抗生素,用于不复杂的病例.
- 抗生素可以减少并发症和住院时间,但复发是令人担忧的.
研究的目的:
- 为了比较抗生素治疗与无并发性急性尾炎的尾切除术.
- 评估症状的消失和并发症的发生率.
主要方法:
- 对平行组随机对照试验 (RCT) 的系统审查.
- 搜索了多个数据库 (CENTRAL,MEDLINE,Embase) 和试验登记册.
- 包括没有并发症的尾炎的成年参与者,比较抗生素与尾切除.
主要成果:
- 死亡率和重大并发症的不确定性,由于证据的确定性非常低.
- 抗生素可能会增加治疗失败率 (76/1000),但会减少伤口感染.
- 大约30.7%的抗生素治疗患者在一年内需要尾切除;证据非常不确定.
结论:
- 对无并发性尾炎的抗生素治疗对于治疗成功和住院的结果是不确定的.
- 在接受抗生素治疗的患者中,很大一部分患者可能需要在以后进行尾切除.
- 抗生素可以减少伤口感染,但会增加负尾切除术的发生率.
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