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Updated: Jun 27, 2025

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通过无的2/3阶段试验设计加速疫苗开发

Jia-Ying Yang1, Guo-Chun Li1, Ying Yuan2

  • 1Department of Public Health, School of Medicine, Nanjing University of Chinese Medicine, Nanjing, China.

Expert review of vaccines
|April 29, 2024
PubMed
概括

一个无的2/3阶段试验设计显著加速疫苗开发,减少试验持续时间和样本大小,同时保持有效性. 这种创新方法对于加快新疫苗,特别是多价值疫苗的批准至关重要.

关键词:
无二/三阶段试验同一初级终点的初级终点.有条件功率的条件功率.组序列设计组的设计.进行中期分析分析.

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