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Updated: Jun 27, 2025

Oncogenic Gene Fusion Detection Using Anchored Multiplex Polymerase Chain Reaction Followed by Next Generation Sequencing
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斯皮茨瘤与ALK重组:一个病例报告和文献综述

S K Lai1, I H Bakrin2, N Abd Rauf3

  • 1Universiti Putra Malaysia, Faculty of Medicine and Health Sciences, Department of Pathology, 43400 Serdang, Selangor, Malaysia. pathsklai@gmail.com.

The Malaysian journal of pathology
|April 29, 2024
PubMed
概括

这项研究报告了一名亚洲儿童罕见的斯皮茨瘤与ALK重组. 通过FISH确认的ALK重组表明良性临床过程,尽管异常特征.

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Conservative Site-specific Recombination and Phase Variation02:53

Conservative Site-specific Recombination and Phase Variation

Because the DNA segments are cut and reorganized in a direction-specific manner, site-specific recombination has emerged as an efficient genetic engineering technique. Flippase and Cyclization recombinases or Flp and Cre, respectively, are two members of the tyrosine recombinase family derived from bacteriophages, that are used to mediate site-specific DNA insertions, deletions, and targeted expression of proteins in mammalian cell lines.
The recognition sites for Cre recombinase called LoxP...
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