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相关概念视频

Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
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Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

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The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
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Psychosis: Goals of Pharmacotherapy01:26

Psychosis: Goals of Pharmacotherapy

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Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
124
Desensitization and Tachyphylaxis01:20

Desensitization and Tachyphylaxis

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Tachyphylaxis is described as a rapid decrease in response to a drug after repeated or continuous administration of the same drug dose. It is a phenomenon where the body becomes less responsive to a particular substance or intervention over time, requiring higher doses or stronger interventions to achieve the same effect. It results from adaptive changes in the body's receptors, signaling pathways, or physiological processes that occur in response to prolonged exposure to a stimulus.
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Hypoglycemia and Glucagon01:15

Hypoglycemia and Glucagon

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Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
257
The Thyroid Gland01:23

The Thyroid Gland

3.9K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
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When hidden steroids cause harm: Secondary adrenal insufficiency from unrecognised exposure.

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相关实验视频

Updated: Jun 27, 2025

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
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Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

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耐火性甲状腺功能低下症 耐火性甲状腺功能低

Y Y Lai1, S C Thambiah2, N Mohamed Mokhtar1

  • 1Hospital Kuala Lumpur, Department of Pathology, Ministry of Health Malaysia.

The Malaysian journal of pathology
|April 29, 2024
PubMed
概括

甲状腺激素 (LT4) 吸收测试可以快速且负担得起地排除在患有持续高甲状腺刺激激素 (TSH) 水平的患者中真正的吸收不良. 这种测试有助于避免不必要的专家转诊,并确认适当的LT4剂量.

科学领域:

  • 内分泌学 在内分泌学.
  • 甲状腺学 甲状腺学
  • 药理动力学 药理动力学

背景情况:

  • 持续高甲状腺刺激激素 (TSH) 尽管超治疗性勒沃西 (LT4) 剂量是一个常见的临床挑战.
  • 这种表现往往促使对LT4吸收不良或不粘附的调查,这是很难确定的.
  • 准确的患者问责制至关重要,但在怀疑不遵守的情况下,很难确认.

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