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Updated: Jun 27, 2025

Peptide Scanning-assisted Identification of a Monoclonal Antibody-recognized Linear B-cell Epitope
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开发一种有效的单链变量片段,识别型在型肝炎病毒E2蛋白中的新型表位,该蛋白限制病毒进入肝细胞

Soma Das1, Padmanava Behera2, Dipeshwari J Shewale3

  • 1Department of Biochemistry, Indian Institute of Science, Bangalore, 560012, India. somad@iisc.ac.in.

Archives of virology
|April 29, 2024
PubMed
概括

研究人员开发了一种基于A8A11抗体的单链可变片段 (scFv). 这种scFv有效地抑制了肝炎C病毒 (HCV) 在细胞培养中的复制,并降低了感染小鼠的病毒载量.

关键词:
抗HCV疗法是一种抗HCV治疗.抗体工程是针对抗体的工程.包裹蛋白质是一种包裹蛋白质.在C型肝炎病毒的感染中,这是一种单克隆抗体.单链变量片段 (scFv) 是指一个单链变量片段.

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