患有心力衰竭和肉症的患者的预后因素:一项观察性回顾性研究
Yasutaka Imamura1, Atsushi Suzuki2, Kazuho Kamishima1
1Department of Cardiology, Rissho Koseikai Kosei Hospital, Tokyo, Japan.
概括
这项研究发现,年龄较大,NYHA类较高,BNP升高和LVEF降低预测了心力衰竭 (HF) 患者的死亡. 密切监测BNP和LVEF对于管理这些患者至关重要.
科学领域:
- 心脏病学 心脏病学
- 老年病的医生 老年病的医生
- 内部医学 内部医学
背景情况:
- 心力衰竭 (HF) 的患病率随着年龄的增长而增加.
- 麻症是HF患者显著的负面预后因素.
- 这项研究调查了患有肉症的HF患者.
研究的目的:
- 为了评估患有HF和肉类的患者的特征.
- 为了确定HF患者的死亡率的预后因素.
- 为了比较HF与减少喷射分数 (HFrEF) 和HF与保存喷射分数 (HFpEF) 在sarcopenic患者之间的结果.
主要方法:
- 通过双能X射线吸收计对256名被诊断为肉症的高频患者进行了回顾性审查.
- 主要终点:所有原因的死亡率.
- 在HFrEF (LVEF < 50%) 和HFpEF (LVEF ≥ 50%) 组之间的特征和预后的比较.
主要成果:
- 83名患者 (32%) 患有HFrEF,173名患者 (68%) 患有HFpEF.
- HFrEF组的高血压率较低,缺血性心脏病的发病率更高,脑中尿素 (BNP) 水平更高.
- 卡普兰-梅尔分析显示,HFrEF组的预后明显较差 (逻辑等级p=0.002).
结论:
- 年龄较大,NYHA类较高,BNP水平升高和LVEF降低是患有肉症的HF患者死亡的独立预测因素.
- 对患有肉症的HF患者的管理需要密切关注BNP和LVEF.
- 这些因素对于改善患者的治疗结果至关重要.
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