膀高度与宽度的比作为一个替代标记,用于非生理储存压力在患有脊髓缩症的儿童
Shrilakshmi Aithal1, Arvind Sinha2, Manish Pathak1
1Department of Pediatric Surgery, All India Institute of Medical Sciences, Jodhpur, Rajasthan, 342005, India.
Pediatric surgery international
|April 29, 2024
概括
囊泡图上的膀高度宽度比 (HWR) 可以帮助识别脊髓缩症儿童的非生理性膀压力. 1.3或更高的HWR表明膀压力升高,有助于临床评估.
科学领域:
- 儿科泌尿外科 儿科泌尿外科
- 神经泌尿病学 神经泌尿病学
- 医疗成像医学成像
背景情况:
- 脊髓疏松症经常导致儿童的神经性膀.
- 尿动力学研究 (UDS) 对于神经性膀管理至关重要,但面临着可用性和解释方面的挑战.
- 在这个群体中,膀形状和尿动力学参数的客观定义有限.
研究的目的:
- 评估膀高度宽度比 (HWR) 在囊泡图上作为查工具.
- 为了识别儿科脊髓障碍症患者的非生理性膀压力.
- 为了将膀形状 (HWR) 与尿动力学参数相关联.
主要方法:
- 对53名为脊柱失明而手术的儿童进行前性评估.
- 同时进行了囊囊造影,超声波和UDS.
- HWR是从最大囊泡测量容量的囊泡图计算的;通过UDS确定的最大排泄器压力 (MDP).
主要成果:
- 在非生理压力的膀中,HWR显著更高 (1.55对1.26,p=0.001).
- 对HWR预测非生理压力的灵敏度和特异性分别为87.5%和48.28%.
- 曲线下的面积 (AUC) 为0.781,截止值HWR为1.3.
结论:
- 膀HWR在囊泡图上提供了膀形状的客观测量.
- 膀形状和膀压力之间存在温和的相关性.
- 在这个人群中,HWR ≥ 1.3 是非生理性膀储存压力的潜在指标.
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