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调节性T细胞的CD39表达在实验性Trypanosoma cruzi感染期间参与CD8+T细胞抑制

Cintia L Araujo Furlan1,2, Santiago Boccardo1,2, Constanza Rodriguez1,2

  • 1Departamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.

PLoS pathogens
|April 29, 2024
PubMed
概括

调节性T细胞 (Tregs) 抑制了对Trypanosoma cruzi感染的保护性免疫力. 阻断Tregs上的CD39增强了CD8+T细胞的反应,改善了小鼠的寄生虫控制.

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