紫外光C原型装置对抗Sporothrix brasiliensis作为表面消毒的潜在物理方法
Anderson Luis Terçola1, Vanice Rodrigues Poester1,2, Lívia Silveira Munhoz1,2
1Laboratório de Micologia, Faculdade de Medicina (FAMED), Universidade Federal Do Rio Grande (FURG), Campus Saúde. Visconde de Paranaguá 102, Centro, Rio Grande, Rio Grande do Sul (RS), 96201-900, Brazil.
概括
紫外线C (UVC) 光有效地使Sporothrix brasiliensis,一种新兴的真菌病原体失活. 这项研究证明了UVC的存在.
科学领域:
- 菌类学 菌类学是指菌类学.
- 传染性疾病 传染性疾病
- 生物技术是生物技术.
背景情况:
- 巴西猫是一种新兴的真菌病原体,具有感染猫的环境污染的风险.
- 有效的表面消毒方法对于控制S. brasiliensis的传播至关重要.
- 关于物理消毒方法的有效性,例如紫外线C (UVC) 光,对S. brasiliensis的有效性存在有限的数据.
研究的目的:
- 为了评估一个便携式UVC装置在抑制Sporothrix brasiliensis的有效性.
- 评估紫外线对S. brasiliensis的酵母和菌阶段的杀菌活性.
主要方法:
- 一个标准化的酵母和菌阶段S. brasiliensis的注射体被暴露在一个原型UVC装置中.
- 测试了三种UVC辐射剂量:3.5mJ/cm2 (1秒),5.25mJ/cm2 (1.5秒) 和329mJ/cm2 (94秒).
- 定量化了殖民地形成单位 (CFU),以确定真菌生存能力的减少.
主要成果:
- 所有测试的UVC剂量都显著降低了S. brasiliensis的酵母和菌阶段的CFU计数.
- 在不同UVC剂量中,平均真菌减少率在78%至100%之间.
- 在329mJ/cm2 (94秒暴露) 时,可以达到对酵母阶段的完全杀菌活性.
结论:
- 紫外线光是一种可行的物理方法,用于消毒被Sporothrix brasiliensis污染的表面.
- 开发的UVC原型为消除病原体提供了一个易于处理和快速的解决方案.
- 进一步的研究可以探索S. brasiliensis控制的临床和环境环境中的UVC应用.
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