新辅助化疗与术后结果的关联在即时的胸前假体乳房重建中
Jae-Min Choi1, Jong-Koo Lee2, Jai-Kyong Pyon2
1From the Department of Plastic and Reconstructive Surgery, Myong-Ji Hospital, Myong-Ji Medical Foundation, Goyang.
Annals of plastic surgery
|April 30, 2024
概括
在立即胸前乳房重建之前的新辅助化疗 (NACT) 似乎是安全的. 这项研究发现,与未接受NACT治疗的患者相比,接受NACT治疗的患者并发症没有显著增加.
科学领域:
- 在瘤学瘤学.
- 整形外科 整形外科 整形外科
- 乳腺癌治疗方法 乳腺癌治疗方法
背景情况:
- 新辅助化疗 (NACT) 随后的乳房切除和立即重建是乳腺癌的关键治疗方法.
- 使用NACT进行子胸部重建的安全性已知,但前胸部重建的安全性不太清楚.
研究的目的:
- 评估接受新辅助化疗 (NACT) 的患者立即胸前乳房重建的安全性和结果.
- 为了确定NACT是否与前胸部重建中术后并发症的增加有关.
主要方法:
- 对343名接受立即胸前植入物基础重建的患者的回顾性审查 (2021年5月至12月).
- 在接受NACT (n=85) 和未接受NACT (n=258) 的患者之间,术后并发症率的比较.
- 用多变量后勤回归和倾向得分匹配来分析NACT与不良结果之间的关联.
主要成果:
- 在NACT和非NACT组之间没有观察到总体或特定并发症率的显著差异.
- 纳克特组的特点包括年龄较小,BMI较高,辅助放射治疗率较高.
- 多变量和倾向分数匹配分析证实,NACT与不良结果没有显著关联.
结论:
- 新辅助化疗似乎不会对手术后的结果产生负面影响,即时的胸前假肢重建.
- 基于胸前植入物的重建可能是接受NACT的患者的安全和可行的选择.
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