风险因素 系统性炎症反应综合征 在皮肤透过肝的胆管透视性胆管透视性胆管透视后的风险因素
Lve Cheng1, Junwei Niu1, Yao Cheng1
1Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Journal of inflammation research
|April 30, 2024
概括
这项研究开发了一种预测模型,用于肝炎症的皮肤透过性肝胆透性胆透症 (PTCSL) 后的全身炎症反应综合征 (SIRS). 该模型使用石头位置和手术前实验室值等因素来识别高风险患者.
科学领域:
- 肝胆道手术是肝胆道的手术.
- 胃肠病学 胃肠病学
- 关键护理医学 关键护理医学
背景情况:
- 肝炎结石症的治疗通常涉及皮肤通透的透肝胆透视性胆透症 (PTCSL).
- 系统性炎症反应综合征 (SIRS) 是PTCSL后的一个潜在并发症.
- 目前缺乏对SIRS后PTCSL的验证预测模型.
研究的目的:
- 为了估计肝病中PTCSL后SIRS的发生率.
- 确定PTCSL后SIRS发展的独立风险因素.
- 构建和验证SIRS发生的预测名录模型.
主要方法:
- 对284次PTCSL治疗肝病的回顾性分析.
- 使用单变量和多变量逻辑回归识别独立的风险因素.
- 构建一个名ogram预测模型并通过ROC曲线评估其准确性.
主要成果:
- 在PTCSL后SIRS的发病率为20.77%.
- 确定的独立风险因素包括:PTCSL治疗次数,结石的位置,手术期间使用上腺素,手术期间穿刺,手术前使用胺转移酶和手术前的总淋巴细胞计数.
- 开发的诺莫格拉姆模型表现出令人满意的预测准确性 (AUC = 0.776).
结论:
- 纳米图模型包含特定的临床和实验室因素,可以预测PTCSL后SIRS风险.
- 该模型有助于临床医生识别患有SIRS风险较高的患者.
- 早期发现有助于及时干预,并有可能改善患者的治疗结果.
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