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SARS-Cov-2 尖峰通过 CEACAM5 和 Galectin-9 之间的相互作用诱导肠道屏障功能障碍

Yingshu Luo1, Zhenling Zhang1, Jiangnan Ren1

  • 1Department of Gastroenterology, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong, China.

Frontiers in immunology
|April 30, 2024
PubMed
概括

在肠道中,SARS-CoV-2尖端蛋白减少了与癌胚抗原相关的细胞粘附分子5 (CEACAM5),导致肠道屏障功能障碍. 这种与Galectin-9的相互作用为严重的COVID-19患者提供了潜在的治疗点.

关键词:
CD4+ T 淋巴细胞在 CEACAM5 中.在 COVID-19 疫情中,盖莱克-9 是一种蛋白质.在SARS-CoV-2病毒中,尖蛋白是最常见的.肠道屏障功能障碍 肠道屏障功能障碍

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