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一个多种多病原体的禽类病毒病爆发事件:调查野生鸟类 - 禽类接口病毒传播的潜力

Scott M Reid¹, Alexander M P Byrne¹, Fabian Z X Lean²

¹Virology Department, Animal and Plant Health Agency (APHA) Weybridge, Addlestone, UK.

Emerging microbes & infections

|April 30, 2024

概括

高致病性禽流感病毒 (HPAIV) H5N8从受感染的家禽传播到野生鸟类,包括乌,乌,和. 这凸显了商业和野生鸟种群之间疾病传播的风险.

科学领域:

兽医病毒学兽医病毒学
野生动物疾病生态学野生动物疾病生态学
鸟类病理学鸟类病理学

背景情况:

高致病性禽流感病毒 (HPAIV) H5N8疫情对家禽和野生鸟类种群构成重大威胁.
了解家禽和野生鸟类之间的传播动态对于疾病控制至关重要.

研究的目的:

调查HPAIV H5N8从商业家禽养殖场传播给野生鸟类的情况.
为了确定涉及H5N8流行病的野生鸟类物种,并评估病毒载量.
为了检查与1型 (APMV-1) 类型的禽类类型型病毒病毒的同时感染.

主要方法:

关于HPAIV H5N8疫情在一个自由养的有机肉场所爆发的案例调查.
在死亡的野生鸟类 (乌,乌,,) 中进行尸检和HPAIV H5N8检测.
组织病理学检查和免疫组织化学检测APMV-1.

主要成果:

在多种野生鸟类中检测到HPAIV H5N8,这些野生鸟类在感染的家禽尸体上食.
羊的病毒载量高于受感染的;的病毒载量高于受感染的;的病毒载量高于受感染的;的病毒载量高于受感染的.
在乌,乌和尸中观察到有限的病毒传播. 在家禽和乌中检测到有毒的APMV-1,没有病变同定位.

结论:

这项研究表明,商业家禽和野生鸟类之间的双向禽病毒病传播.
强调生物安全措施的重要性,如生物分离和限制访问,在高HPAIV感染压力期间.
强调野生鸟类作为HPAIV的潜在放大器和传播者的作用.

关键词:

高致病性禽流感病毒 (HPAIV); H5N8; 类 2.3.4.4b; 多种多种.禽类类型1类型的类型1类型的类型1类型的类型1类型的类型1类型的类型1类型的类型1类型的类型1类型的类型1类型的类型1类型的类型1类型的类型1类型的类型1类型的类型1类型的类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1类型1

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