根据轻度和中度膝关节骨关节炎的膝关节疼痛,肌肉强度下降2年和阴道和软骨体积损失之间的关系
Hui Zhang1, Tao Shuai, Junqing Wang
1From the Department of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China (HZ, JW, KL, YN); West China Biomedical Big Data Center, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China (HZ, JW); Department of Radiology, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China (TS); Med-X Center for Informatics, Sichuan University, Chengdu, Sichuan, China (KL); and Shanghai Artificial Intelligence Laboratory, Shanghai, China (KL).
肌肉力量的下降与膝关节骨关节炎患者的阴囊退化有关,这些患者有明显的疼痛. 保持四头骨-腿筋平衡可能会保护那些四头骨较弱和严重疼痛的人的膝关节功能.
科学领域:
- 整形外科 整形外科 整形外科
- 类风湿病学 类风湿病学
- 运动医学 运动医学
背景情况:
- 膝关节骨关节炎 (OA) 是一种退行性关节疾病,其特征是软骨损失和疼痛.
- 肌肉力量,特别是四头肌,对于膝关节的稳定性和功能至关重要.
- 在轻度至中度病例中,肌肉强度的变化与结构性OA进展之间的关系需要进一步阐明.
研究的目的:
- 调查轻度至中度膝关节OA的个体膝关节肌肉强度和软骨/半径状况2年变化之间的关联.
- 确定膝关节疼痛水平如何影响肌肉强度变化和OA进展之间的关系.
主要方法:
- 对来自骨关节炎倡议的279名参与者的回顾性分析.
- 使用西安大略省麦克马斯特大学骨关节炎指数 (WOMAC) 评估疼痛和功能.
- 测量5个膝关节肌肉强度参数 (延伸器,器,比率) 通过同位测强度测试和膝关节结构变化 (半月膜,软骨) 使用MRI超过2年.
主要成果:
- 膝关节OA的进展涉及骨骨软骨的损失和阴茎退化.
- 在WOMAC疼痛>2的参与者中,延伸器强度的降低与中间半月膜体积损失相关.
- 延伸器/曲器比率的变化与WOMAC功能得分在2年内的变化有关.
结论:
- 四头肌强度的下降与膝盖骨关节炎患者中枢阴囊变性正相关,这些患者经历了明显的疼痛.
- 四头肌-腿筋肌肉平衡可能为四头肌力量减弱和严重疼痛的人提供对膝关节功能的保护作用.
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