系统性红斑狼的口腔病变:一个合作的拉丁美洲研究
José Alcides Almeida de Arruda1, Mariana Villarroel-Dorrego2, Clara Herrera Freire1
1Department of Oral Diagnosis and Pathology, School of Dentistry, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Lupus
|April 30, 2024
概括
系统性红斑狼 (SLE) 可以引起各种口腔病变,通常单独出现. 早期口腔检查对于诊断这种自身免疫性疾病和及时开始治疗至关重要.
科学领域:
- 口腔病理学 口腔病理学
- 自身免疫性疾病是一种自身免疫性疾病.
- 皮肤病学 皮肤病学
背景情况:
- 系统性红斑狼 (SLE) 是一种复杂的自身免疫性疾病,影响多个器官,包括口腔粘膜.
- SLE的口腔表现呈现出广泛的病变,使诊断复杂化,特别是当孤立时.
- 了解这些口腔病变对于早期SLE检测和管理至关重要.
研究的目的:
- 描述SLE患者口腔病变的临床和病理特征.
- 分析不同拉丁美洲国家的口腔病变的流行和表现.
主要方法:
- 一项以记录为基础的协作研究,涉及11个口腔和大面部病理学和医学服务.
- 从70名被诊断患有SLE并呈现口腔病变的患者收集的数据.
- 分析了口腔病变的临床病理学概况.
主要成果:
- 大多数患者是女性 (75.7%) 和白人 (62.1%),平均年龄为38.4岁.
- 硬/软口腔是最常见的部位 (32.0%),,侵蚀和白色病变是常见的表现.
- 单独的口腔病变发生在65.2%的病例中,突出显示了它们的诊断意义.
结论:
- 在SLE中,口腔病变表现出不同的临床和病理学特征.
- 无法解释的口腔变化可能意味着一种潜在的系统性疾病,如SLE.
- 包括定期口腔检查在内的多学科方法对于识别和管理与SLE相关的口腔病变至关重要.
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