重症患者的气溶药物治疗 (Aero-in-ICU研究):一个多中心前性观察队列研究
Sanjay Singhal1, Mohan Gurjar2, Jyoti Narayan Sahoo3
1Pulmonary Medicine, All India Institute of Medical Science, Rajkot, Gujarat, India.
Lung India : official organ of Indian Chest Society
|April 30, 2024
概括
气溶治疗在印度ICU中很常见,支气管扩展器和喷气式雾化器是最常见的. 实践的差异很大,这表明在重症监护机构需要标准化的协议.
科学领域:
- 临界护理医学 临界护理医学
- 呼吸系统疗法 呼吸系统疗法
- 药理学 药理学是指药理学的学科.
背景情况:
- 气溶疗法在临床实践中越来越多地使用,这是由于对药物/设备的理解和可用性得到了改善.
- 关于全球重症患者的气溶治疗实践的数据有限,特别是在印度.
研究的目的:
- 调查印度重症监护室 (ICU) 住院的重症患者的气溶治疗现有实践模式.
主要方法:
- 一项多中心,前性观察性研究在印度九个中心进行了四周的时间.
- 使用人工气道和/或通风 (侵入性或非侵入性) 的成年患者被招募并随访14天或直到ICU出院/死亡.
- 收集的数据包括呼吸辅助,药物类型和在治疗期间使用的气溶产生的设备.
主要成果:
- 在218名注册患者中,72.48%接受了气溶疗法,共计4884次.
- 支气管扩展剂是使用最频繁的单一药物 (59%). 喷射雾化器是最常见的设备,其次是超声波和振动网状发电机.
- 在62.7%的病例中,气溶治疗是在侵入性机械通风 (IMV) 期间进行的,而在30.2%的病例中,非侵入性通风 (NIV) 期间进行. 呼吸器设置在治疗期间很少被调整.
结论:
- 气溶疗法经常用于印度ICU的重症患者,但实践显示出显著的差异.
- 支气管扩展剂是主要的药物,喷气式雾化器是最常用的设备.
- 这些发现突出了对标准化指导方针的需求,以优化在重症监护中的气溶治疗.
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