在分阶段单心室重建过程中,主动脉肺动脉附带和肺动脉发育的关系
Helena Staehler1,2,3, Thibault Schaeffer1,2,3, Stanimir Georgiev4
1Department of Congenital and Pediatric Heart Surgery, German Heart Center Munich, Technische Universität München, Munich, Germany.
Pediatric cardiology
|April 30, 2024
概括
在II阶段的息治疗中,心肺动脉附带体对肺动脉大小没有影响. 然而,这些附带资产与Fontan完成时不发达的肺动脉有关,特别是在干预后.
科学领域:
- 心血管外科心血管外科
- 儿童心脏病学 儿童心脏病学
- 遗传性心脏病是一种先天性心脏病.
背景情况:
- 阶段性缓解是复杂的先天性心脏缺陷的常见方法.
- 动脉肺附带病可以在缓解期间发展,并可能影响肺动脉的生长.
- 了解这种关系对于优化手术结果至关重要.
研究的目的:
- 为了研究大动脉肺附带体和中枢肺动脉发育之间的关联.
- 评估干预性关闭主动脉肺附带体对肺动脉指数的影响.
主要方法:
- 对287名接受分阶段息治疗的患者的回顾性分析 (双向腔肺突变和全腔肺连接).
- 肺动脉指数是根据可用的血管图计算的.
- 确定了心肺血管的抵押品,并记录了干预状态.
主要成果:
- 在II阶段,有16%的患者呈现出动脉肺附带,而在全腔肺连接时,这一比例为46%.
- 在早期的肺动脉附带体和II期肺动脉指数之间没有发现任何关联.
- 在Fontan完成之前的抵押与下肺动脉指数相关.
- 在全腔肺连接之前的干预性关闭与Fontan完成时较小的肺动脉有关.
结论:
- 动脉肺附带不妨碍肺动脉的发展通过II阶段的息.
- 脉动动脉肺附带体的存在与在Fontan完成时肺动脉发育不足有关.
- 这些附带的干预性关闭可能与肺动脉大小的减少有关.
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