乳腺癌查:美国预防服务工作组的证据报告和系统审查
Jillian T Henderson1, Elizabeth M Webber1, Meghan S Weyrich2
1Kaiser Permanente Evidence-based Practice Center, Center for Health Research, Portland, Oregon.
JAMA
|April 30, 2024
概括
目前的乳腺癌查证据是不确定的. 需要对最佳查年龄,间隔和减少死亡风险的方法进行更多研究.
科学领域:
- 癌症学
- 放射学
- 预防医学
背景情况:
- 乳腺癌仍然是美国女性的主要死亡原因.
- 查性乳房扫描可以降低死亡风险,但最佳策略尚不清楚.
研究的目的:
- 对美国预防服务工作组的不同乳腺癌查策略进行比较的研究进行审查.
主要方法:
- 随机临床试验和非随机研究的系统审查.
- 通过MEDLINE和Cochrane图书馆的文献搜索到2022年8月,并通过2024年3月进行监视.
- 从公平和优质的研究中提取和综合数据.
主要成果:
- 在74岁以后死亡的证据有限.
- 数字乳腺图解 (DBT) 在间隔癌症中没有显著差异,但回忆率较低.
- 补充查 (MRI,超声波) 显示混合结果,错误阳性增加.
结论:
- 对乳腺癌查策略进行比较的证据是不确定的.
- 关键研究是不完整的,很少有人报告必要的死亡结果.
- 需要进一步研究以建立最佳查准则.
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