饮料消费与2型糖尿病患者中微血管并发症风险之间的关联
Xiaoyu Lin1, Kai Zhu1, Zixin Qiu1
1Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, Ministry of Education Key Lab of Environment and Health, and State Key Laboratory of Environment Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
The Journal of clinical endocrinology and metabolism
|April 30, 2024
概括
人工甜味饮料 (ASB) 和含糖甜味饮料 (SSB) 的摄入量较高与2型糖尿病 (T2D) 中微血管并发症的增加有关. 用茶或咖啡代替这些可以降低风险.
科学领域:
- 内分泌学和新陈代谢学
- 营养流行病学 营养流行病学
- 心血管健康 心血管健康
背景情况:
- 2型糖尿病 (T2D) 中饮料摄入量和微血管并发症之间的联系仍然不清楚.
- 了解这些关联对于管理糖尿病相关的健康风险至关重要.
研究的目的:
- 检查各种饮料消费与T2D成年人微血管并发症风险之间的关系.
- 研究的人工甜味饮料 (ASB),糖甜味饮料 (SSB),茶,咖啡,天然果汁和酸奶.
主要方法:
- 一项包括6676名英国生物库参与者在内的队列研究,T2D,在基线没有并发症.
- 考克斯比例危险模型用于评估饮料消费和并发症风险,平均随访时间为11.7年.
主要成果:
- 增加ASB和SSB的消费量与更高的微血管并发症风险呈现出线性关联.
- 每天消耗≥2.0单位的ASB或SSB与风险增加相关 (HR分别为1.44和1.32).
- 饮茶量较高 (≥4.0单位/天) 与糖尿病视网膜病变风险降低有关 (HR 0.72). 用茶或咖啡代替ASB/SSB,风险降低了16-28%.
结论:
- 较高的ASB和SSB摄入量与T2D成年人的微血管并发症风险增加有关.
- 茶和咖啡的消费可能会提供保护作用,这表明潜在的饮食修改可以降低风险.
相关概念视频
Diabetes: Symptoms, Diagnosis, and Complications
526
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
526
Carbohydrate Metabolism
11.1K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
11.1K
Pathophysiology of Diabetes
922
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
922
Diabetes Mellitus: Overview and Type I Subtype
2.6K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.6K
Psychoneuroimmunology: Diabetes and Cancer
28
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
28
Diabetes: Management and Pharmacotherapy
268
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
268


