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Updated: Jun 27, 2025

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一种新的双价相互作用模式是Pin1介导蛋白激酶C调节的非催化机制的基础

Xiao-Ru Chen1, Karuna Dixit1, Yuan Yang1

  • 1Department of Biochemistry & Biophysics, Texas A&M University, College Station, United States.

eLife
|April 30, 2024
PubMed
概括

Pin1调节蛋白激酶C (PKC) 的活性,不是通过异构化,而是通过与其C端尾部结合. 这种非催化相互作用揭示了调节AGC激酶的新机制.

关键词:
Pin1 基-基异构酶是什么?这是一种双价结合.人类 人类 人类 人类 人类 人类 人类分子生物物理学分子生物物理学非催化机制的非催化机制蛋白质激酶 C 的蛋白质激酶 C.蛋白质激酶C降解降解信号传输 信号传输结构生物学结构生物学

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