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Updated: Jun 27, 2025

Optimization of Crystal Growth for Neutron Macromolecular Crystallography
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晶体工程中的Synthon方法,用于调节胺的有机盐中的物理化学特性

Anila M Menon1, Nagamalli Naga Sidhartha2, Ipsha Shruti1

  • 1Department of Chemistry, IISER Bhopal, Bhopal Bypass Road, Bhopal, Madhya Pradesh 462066, India.

Molecular pharmaceutics
|April 30, 2024
PubMed
概括

这项研究通过机械化学研磨与辅助剂创造了新的固体形式,提高了propamide (CPA) 的生物利用性. 这些新的CPA盐和共晶体显著提高了溶解度和溶解率,从而在老鼠中产生了更好的药理动力学特性.

关键词:
生物可用性 生物可用性晶盐是什么意思晶盐水合物化物形状的调整和形状的变化晶体包装的使用方法溶解溶解是一种通过联结,形成联结.药物动力学 药物动力学盐 盐 盐 盐 盐 盐 盐 盐 盐溶解度 溶解度 溶解度 溶解度

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