国家睡眠研究资源:使数据可查找,可访问,可互操作,可重复使用,并促进睡眠科学
Ying Zhang1, Matthew Kim2, Michael Prerau1
1Division of Sleep Medicine and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Sleep
|April 30, 2024
概括
国家睡眠研究资源 (NSRR) 提供安全访问各种睡眠研究数据,通过标准化和协调解决数据异质性. 这促进了有效的睡眠和昼夜研究,使数据易于查找,可访问,可互操作和可重复使用.
科学领域:
- 睡眠医学和研究研究
- 数据科学和生物信息学
- 生物医学信息学 生物医学信息学
背景情况:
- 睡眠障碍研究受到来自各种收集和注释方法的数据异质性的挑战.
- 分享睡眠研究数据至关重要,但由于数据格式和定义的不一致性而受到阻碍.
- 国家心脏,肺和血液研究所 (NHLBI) 支持国家睡眠研究资源 (NSRR) 集中和标准化睡眠数据.
研究的目的:
- 为国家睡眠研究资源 (NSRR) 提供全面的概述.
- 描述NSRR用于解决数据异质性和促进数据共享的策略.
- 突出NSRR在推进睡眠和昼夜研究中的作用.
主要方法:
- 实施数据处理协议,确保无标识和符合FAIR原则.
- 使用组合编码方案开发了标准化的睡眠术语.
- 协调常用的变量,并开发用于信号处理标准化的计算工具.
主要成果:
- 建立了一个安全的,集中存储库,提供访问多睡眠学,动图学,人口统计学和患者报告的结果.
- 通过标准化术语,元数据,变量协调和信号处理工具成功解决了数据异质性.
- 利用外部资源,为数据协调提供特定领域的方法.
结论:
- 通过提供可访问,高质量和协调的数据集,NSRR增强了睡眠和昼夜研究.
- 标准化和协调是克服睡眠数据共享障碍的关键.
- 在数据标准化和共享方面的进一步努力是睡眠医学领域的机会.
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