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Updated: Jun 23, 2026

Detection of Rare Genomic Variants from Pooled Sequencing Using SPLINTER
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Detection of Rare Genomic Variants from Pooled Sequencing Using SPLINTER

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MPH:用于定量遗传变异的大规模基因组分割的快速REML

Jicai Jiang1

  • 1Department of Animal Science, North Carolina State University, Raleigh, NC 27695, United States.

Bioinformatics (Oxford, England)
|April 30, 2024
PubMed
概括

一个新的软件工具MPH改善了基因组分区,用于分析农场动物的复杂特征. 与现有方法相比,它为大型数据集提供了更高的速度和效率.

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相关概念视频

Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...