患有黄斑相关疼痛的患者中自主功能循环变化:心率可变性分析
Peng Mao1, Hui-Min Hu2, Ran Li2
1Department of Pain Medicine, China-Japan Friendship Hospital, Beijing, China.
Brain and behavior
|April 30, 2024
概括
关联疼痛 (ZAP) 损害了自主神经系统 (ANS) 功能,特别是副交感活动. 患有ZAP的患者在夜间经历了心率变化降低和ANS反应减弱.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 自主神经科学 自主神经科学
背景情况:
- 疹相关疼痛 (ZAP) 是继疹感染后的一种神经病症.
- 自主神经系统 (ANS) 功能障碍可以显著影响整体健康和福祉.
- 昼夜节律在调节生理过程中起着至关重要的作用,包括ANS活动.
研究的目的:
- 为了研究在患有带相关疼痛 (ZAP) 的患者中自主功能的昼夜变化.
- 为了在24小时内比较ZAP患者和健康对照组之间的心率变化 (HRV) 参数.
主要方法:
- 对37名ZAP患者和37名健康志愿者进行了24小时的霍尔特监测.
- 进行了心率变化 (HRV) 的时间和频率域分析.
- 在不同时间段 (日夜) 中,ZAP组和对照组之间的HRV参数的比较.
主要成果:
- 与对照组相比,ZAP患者的平均心率显著增加和HRV参数 (SDNN,RMSSD,LF,HF) 降低.
- 虽然对照组显示SDNN和RMSSD的正常昼夜变化,但ZAP患者的夜间SDNN减少,RMSSD白天变化减弱.
- 两组之间没有观察到LF/HF比率的显著差异.
结论:
- 关联疼痛 (ZAP) 与总体自主神经系统 (ANS) 功能下降有关.
- 在ZAP患者中,ANS的副交感成分特别受到影响.
- 患有ZAP的患者在夜间的时间表现出了寄生交感优势的丧失和ANS调节的受损.
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