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Updated: Jun 27, 2025

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一种高效的精确基因组编辑方法,使用CRISPR在iPSC中进行编辑.

Avinash Singh1, G Dalton Smedley1, Jamee-Grace Rose1

  • 1Department of Neurology, University of Minnesota, Twin Cities, Minneapolis, MN, USA.

Scientific reports
|April 30, 2024
PubMed
概括

在人类诱导多能干细胞 (iPSCs) 中产生精确的遗传变化现在更快,更容易. 使用CRISPR技术的新协议显著提高了创建异构细胞系的成功率.

关键词:
克里斯普尔是什么意思?克里斯普尔是什么意思?基因编辑 基因编辑高效率的高效率的高效率.单个核酸的多态性.这就是 iPSC 的意义.

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相关概念视频

CRISPR01:59

CRISPR

Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced...
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