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扩展残疾状况尺度与行走,视觉和认知测试的整合

Alessio Sarnataro¹, Nunzia Cuomo², Cinzia Valeria Russo²

¹Department of Neurosciences and Reproductive and Odontostomatological Sciences, University "Federico II", Via Pansini, 5, 80131, Naples, Italy. sarnataromd@gmail.com.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

|April 30, 2024

概括

客观测试显著提高了多发性硬化症 (MS) 患者扩展残疾状态量表 (EDSS) 的准确性. 这种精细的EDSS评估提供了更精确的残疾进展指标.

科学领域:

神经学神经学
临床评估临床评估
多发性硬化症研究研究

背景情况:

扩展残疾状态量表 (EDSS) 是对多发性硬化症 (MS) 残疾的标准衡量标准.
目前的EDSS计算依赖于神经学检查和自我报告的表现,可能导致不准确的功能系统分数 (FSs).

研究的目的:

为了比较来自常规神经学检查的EDSS分数与在特定功能测试后获得的EDSS分数.
评估客观测量对MS患者EDSS和FS评估的影响.

主要方法:

670名多发性硬化患者接受了标准的神经学咨询.
客观评估包括视觉敏度 (光型表),行走 (轮表) 和认知功能 (MS国际认知评估简报 - BICAMS).
综合EDSS (iEDSS) 是使用精制的FS值计算出来的,并与标准EDSS进行比较.

主要成果:

客观FS评估 (视觉,大脑,行走) 的得分明显高于自我报告的数据.
平均iEDSS显著高于标准EDSS.
客观测试改变了大多数患者的EDSS: 31%的视觉,10%的认知,35%的行走,59%的三个.

结论:

在近三分之二的案例中,对FS的客观测量会导致更准确的EDSS得分.
这种更高的准确性可以改善患者的评估,特别是在MS的过渡或渐进阶段.
实施客观测试可以更可靠地评估MS中神经功能.

关键词:

步行旅行 (Ambulation) 是一种行走方式.认知认知是一种认知.障碍障碍是指残疾人的残疾.测量方法测量方法视觉视觉视觉视觉视觉视觉视觉

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